From North: Start out going west on State St / CR-D toward Main St S / CR-DH. Turn left onto Main St S / CR-DH. Turn right onto Gaarder Rd W / CR-DH. Turn left onto Holmen Dr S / WI-35 BR / Great River Rd. Continue to follow WI-35 BR S / Great River Rd. Merge onto US-53 S toward Onalaska / La Crosse. Merge onto I-90 W / US-53 S toward Minnesota. Merge onto US-53 S via Exit 3 toward La Crosse Turn left onto Rose St / US-53 N / Great River Rd. End at 2150 Rose St.
From South: Start out going southwest on WI-56 toward Main St. Turn sharp right onto Main St. Turn right onto WI-35 / Great River Rd. Continue to follow WI-35 / Great River Rd. Continue to follow WI-35 N. Turn slight right onto West Ave S / WI-35. Continue to follow WI-35. Turn left onto Moore St. Turn right onto Rose St / US-53 N / Great River Rd. End at 2150 Rose St.
From East: Start out going northwest on WI-33 / South St toward Front St / CR-U. Turn left onto WI-33 / Front St. Continue to follow WI-33. Turn right onto WI-162 N. Merge onto I-90 W via the ramp on the left toward La Crosse. Merge onto US-53 S via EXIT 3 toward LA CROSSE. Turn left onto Rose St / US-53 N / Great River Rd. End at 2150 Rose St.
From West: Start out going east on S 1st ST toward S Walnut St. Turn left onto S Walnut St. Turn right onto MAIN ST. Turn right onto S Chestnut St. Turn sharp left onto US-14 W / US-61 N. Merge onto I-90 E toward La Crosse / Madison Crossing into Wisconsin. Take the George St / WI-35 S exit S exit-EXIT 3A. Merge onto Rose St / US-53 N / Great River Rd. Turn left onto Rose St / US-53 N / Great River Rd. End at 2150 Rose St.
From Airport: Start out going south. Turn right. Turn left onto Airport Rd. Turn left onto Fanta Reed Rd W / CR-B. Turn right onto Dawson Ave / Fanta Reed Rd W / CR-B S. Continue to follow Dawson Ave / CR-B S. Merge onto I-90 E toward La Crosse / Madison. Take the George St / WI-35 S exit EXIT 3A. Merge onto Rose St / US-53 N / Great River Rd. Turn left onto Rose St / US-53 N / Great River Rd. End at 2150 Rose St.